Protein name:
Dual oxidase 1 ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with TXNDC11, TPO and CYBA.
Function:
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Subcellular Location:
Apical cell membrane
Multi-pass membrane protein
Localizes to the apical membrane of epithelial cells.
Protein Attributes:
50:
MAVYSAVAWI | LLFGVLASLG | AQNPVSWEVQ | RFDGWYNNLM | EHRWGSKGSR |
100:
LQRLVPASYA | DGVYQPLREP | YLPNPRHLSN | RVMRGPAGQP | SLRNRTVLGV |
150:
FFGYHVLSDL | VSVETPGCPA | EFLNIYIPRG | DPVFDPDKRG | NVVLPFQRSR |
200:
WDRSTGQSPS | NPRDLTNQVT | GWLDGSAIYG | SSHSWSDTLR | SFSGGQLASG |
250:
PDPAFPRNSQ | NSLLMWMAPD | PATGQGGPQG | LYAFGAQRGN | REPFLQALGL |
300:
LWFRYHNLCA | KRLAQEHPHW | GDEELFQHAR | KRVIATYQNI | AMYEWLPSFL |
350:
KQTPPEYPGY | HPFLDPSISP | EFVVASEQFL | STMVPPGVYM | RNASCHFQGI |
400:
ANRNSSVSGA | LRVCNSYWSR | ENPKLQRAED | VDALLLGMAS | QIAEREDHLV |
450:
VEDVQDFWPG | PLKFSRTDYL | ASCLQRGRDL | GLPSYTKARE | ALGLPPVSHW |
500:
QDINPALSRS | NGTVLEATAA | LYNQDLSRLE | LLAGGLLESH | GDPGPLFSAI |
550:
VLDQFVRLRD | GDRYWFENNR | NGLFSKEEIA | EIRNTSLRDI | LVAVTNVDPS |
600:
ALQPSVFFWL | AGDPCPQPSQ | LSTQGLPACA | PLFVRDYFKG | SGFGFGLTIG |
650:
TLCCFPLVSL | LSAWIVARLR | MRNFKRLQRQ | DRQSIMCEKL | VGGVEALEWQ |
700:
GRKEPCRPVL | VHLQPGQIRV | VDGRLTVLRT | IQLRPPQQVN | LILSSNRGRR |
750:
TLLLKIPKEY | DLVLLFNMEE | ERQALVENIR | AALKENGLSF | QEWELREQEL |
800:
MRAAVTRQQR | GHLLETFFRH | LFSQVLDINQ | ADAGTLPLDS | STKVREALTC |
850:
ELSRAEFADS | LGLKPQDMFV | ESMFSLADKD | GNGYLSFREF | LDILVVFMKG |
900:
SPEEKSRLMF | RMYDFDGNGL | ISKDEFIRML | RSFIEISNNC | LSKDQLAEVV |
950:
ESMFRESGFQ | DKEELTWEDF | HFMLRDHDSD | LRFTQLCVKG | VEVPEVIKNL |
1000:
CRRASYISQE | KICPSPRMSA | HCARNNTKTA | SSPQRLQCPV | DTDPPQEIRR |
1050:
RFGKKVTSFQ | PLLFTEAHRE | KFQRSRRHQT | VQQFKRFIEN | YRRHIGCVAV |
1100:
FYTITGALFL | ERAYYYAFAA | HHSGITDTTR | VGIILSRGTA | ASISFMFSYI |
1150:
LLTMCRNLIT | FLRETFLNRY | IPFDAAVDFH | RFIASTAIIL | TVLHSAGHVV |
1200:
NVYLFSISPL | SVLSCLFPDL | FHDDGSEFPQ | KYYWWFFQTV | PGLTGVLLLL |
1250:
ALAIMYVFAS | HHFRRRSFRG | FWLTHHLYIF | LYILLIIHGS | FALIQMPRFH |
1300:
IFFLVPAIIY | VGDKLVSLSR | KKVEISVVKA | ELLPSGVTHL | RFQRPQGFEY |
1350:
KSGQWVRIAC | LALGTTEYHP | FTLTSAPHED | TLSLHIRAAG | PWTTRLREIY |
1400:
SPPTGDTCAR | YPKLYLDGPF | GEGHQEWHKF | EVSVLVGAGI | GVTPFASILK |
1450:
DLVFKSSVSC | QVFCKKIYFI | WVTRTQRQFE | WLADIIREVE | ENDSRDLVSV |
1500:
HIYITQLAEK | FDLRTTMLYI | CERHFQKVLN | RSLFTGLRSV | THFGRPPFEP |
1550:
FFNSLQEVHP | QVRKIGVFSC | GPPGMTKNVE | KACQLINKQD | RTHFSHHYEN |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Dog
Pig
ELISA Kit for Rat Dual oxidase 1
ELISA Kit for Rat Dual oxidase 1
ELISA Kit for Rat Dual oxidase 1
ELISA Kit for Rat Dual oxidase 1
CLIA Kit for Rat Dual oxidase 1
CLIA Kit for Rat Dual oxidase 1
CLIA Kit for Rat Dual oxidase 1
CLIA Kit for Rat Dual oxidase 1
Polyclonal Antibody for Rat Dual oxidase 1
Polyclonal Antibody for Rat Dual oxidase 1
Polyclonal Antibody for Rat Dual oxidase 1
Polyclonal Antibody for Rat Dual oxidase 1
Monoclonal Antibody for Rat Dual oxidase 1
Monoclonal Antibody for Rat Dual oxidase 1
Monoclonal Antibody for Rat Dual oxidase 1
Monoclonal Antibody for Rat Dual oxidase 1
Protein for Rat Dual oxidase 1
Protein for Rat Dual oxidase 1
Protein for Rat Dual oxidase 1
Protein for Rat Dual oxidase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Fischer 344 .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY